Chile is divided into 15 regions, of which the most populated are Region Metropolitana, Valparaiso and Bio Bio. Major cities are Santiago (pop. 5,428,590), Valparaíso (pop. 803,683), Concepcion (pop. 670,381), La Serena
296,253, Antofagasta (pop. 285,255), and Temuco (pop. 260,878). All major cities have operating airports and good hotel infrastructure.